Bushra Khan
Bioinformatics & Computational Biology — interactive visual explorations of core concepts.
// Syllabus Explained
The DNA
An interactive 3D visualizer covering DNA structure, base pairing, nucleotides, histones, grooves, and bioinformatics applications.
View Project → Domain 1 · Topic 1Replication
An interactive visualizer exploring the DNA replication machinery, semi-conservative replication, leading/lagging strands, and connections to computational biology.
View Project → Domain 1 · Topic 2Fidelity Safeguards
Explore the 3-layer security system of DNA replication: active-site geometry, proofreading, and mismatch repair, preventing catastrophic mutations.
View Project → Domain 1 · Topic 3Okazaki Fragments
Understand the synthesis of the lagging strand, Okazaki fragment processing, DNA Ligase, and their critical importance to bioinformatics.
View Project → Domain 1 · Topic 4Fidelity Begins Before Biology
Discover the physical and chemical principles that govern DNA base pairing, ΔG, and why true mutations are computationally rare.
View Project → Domain 1 · Topic 5The Physics of Base Pairing
Nucleotide selection isn't magic. It is a strict mathematical consequence of atomic geometry, electrostatics, and thermodynamics.
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